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REVIA does not interfere with thin-layergas-liquidand high pressure liquid chromatographic methods which may be used for the separation and detection of morphinemethadone or quinine in the urineREVIA may or may not interfere with enzymatic methods for the detection of opioids depending on the specificity of the testPlease consult the test manufacturer for specific details.

To reduce the risk of precipitated withdrawal in patients dependent on opioidsor exacerbation of a preexisting subclinical withdrawal syndromeopioid-dependent patientsincluding those being treated for alcohol dependenceshould be opioid-freeincluding tramadolbefore starting REVIA treatmentAn opioid-free interval of a minimum of 7 to 10 days is recommended for patients previously dependent on short-acting opioids.

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