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Renal impairmentLabeling frommanufacturer does not provide dosage adjustment information.
If your doctor has directed you to use this medicationyour doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for themDo not startstopor change the dosage of any medicine before checking with your doctorhealth care provider or pharmacist first.
Numerous antihypertensive drugsfrom a variety of pharmacologic classes and with different mechanisms of actionhave been shown in randomized controlled trials to reduce cardiovascular morbidity and mortalityand it can be concluded that it is blood pressure reductionand not some other pharmacologic property of the drugsthat is largely responsible for those benefitsThe largest and most consistent cardiovascular outcome benefit has been a reduction in the risk of strokebut reductions in myocardial infarction and cardiovascular mortality also have been seen regularly.
It is important to continue taking this medication even if you feel wellMost people with high blood pressure do not feel sick.
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