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Methotrexate can lower blood cells that help your body fight infections and help your blood to clot.

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Tell your doctor right away if you have any serious side effectsincludingmouth soresdiarrheasigns of anemiasuch as unusual tirednesspale skinsigns of liver problemssuch as dark urinepersistent nausea/vomitingstomach/abdominal painyellowing eyes/skineasy bruising/bleedingblack stoolsenlarged glands/lymph nodesbone painunusual pain and discoloration of the skinsigns of kidney problemssuch as change in the amount of urinedry coughmuscle weakness.

Live vaccinesWhen used with methotrexatelive vaccines raise your risk of infectionThe vaccine may also not work as wellLive vaccinessuch as FluMistare vaccines that contain small amounts of livebut weakenedviruses

For psoriasismethotrexate slows down how fast your body produces the top layer of your skinThis helps to treat the symptoms of psoriasiswhich include dryitchy patches of skin.

Before taking methotrexatetell your doctor or pharmacist if you are allergic to itor if you have any other allergiesThis product may contain inactive ingredientswhich can cause allergic reactions or other problemsTalk to your pharmacist for more details.

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