There is a copegus pregnancy registry that collects information about pregnancy outcomes of female patients and female partners of male patients exposed to ribavirin.
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Ribavirin may cause a significant reduction in red blood cell count which can cause anemiaAnemia can worsen heart disease and may cause heart attacks which may lead to deathPeople who have a history of heart disease should not be treated with ribavirin1,2.
If you are a mando not take ribavirin if your female sexual partner is pregnantAn unborn baby could also be harmed if a man fathers the child while he is taking ribavirin.
Alpha interferonsincluding Pegasysmaycause or aggravate fatal or life-threatening neuropsychiatricautoimmuneischemicand infectious disordersPatients should be monitored closely with periodic clinical and laboratory evaluationsPatients with persistently severe or worsening signs or symptoms of these conditions should be withdrawn from therapyIn manybut not all casesthese disorders resolve after stopping Pegasys therapyCopegus may cause birth defectsExtreme care must be taken to avoid pregnancy in female patients and in female partners of male patients taking Pegasys and Copegus combination therapyRibavirin causes hemolytic anemiaThe anemia associated with ribavirin therapy may result in worsening of cardiac disease.
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