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Meperidine demerol ; diet pills, stimulants, cold or allergy medicines, adhd medication; migraine or cluster headache medication such as almotriptan axert , frovatriptan frova , naratriptan amerge , rizatriptan maxalt , sumatriptan imitrex, treximet , or zolmitriptan zomig ; medication to treat parkinson s disease or restless leg syndrome, such as carbidopa or levodopa lodosyn, parcopa, sinemet , pramipexole mirapex , or ropinorole requip ; an ssri antidepressant such as citalopram celexa , escitalopram lexapro , fluoxetine prozac, sarafem, symbyax , fluvoxamine luvox , paroxetine paxil , or sertraline zoloft ; an snri antidepressant such as venlafaxine effexor , desvenlafaxine pristiq , or duloxetine cymbalta ; a tricyclic antidepressant such as amitriptyline elavil, vanatrip, limbitrol , clomipramine anafranil , desipramine norpramin , doxepin sinequan , imipramine janimine, tofranil , nortriptyline pamelor , protriptyline vivactil , or trimipramine surmontil ; or other medications used to treat depression, anxiety, and other psychiatric conditions, such as bupropion wellbutrin, zyban, aplenzin , buspirone buspar , maprotiline ludiomil , mirtazapine remeron , nefazodone, trazodone desyrel, oleptro , or vilazodone viibryd .

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After taking this medicine for long periods of timesuch as a year or moresome people suddenly lose the ability to moveThis loss of movement may last from a few minutes to several hoursThe person is then able to move as beforeThis condition may unexpectedly occur again and againThis problem is called theon-offeffectYour doctor may prescribe you a stronger dose of SINEMET or may ask you to take it more frequentlyYour doctor may need to prescribe you a different medicine.

Since its decarboxylase inhibiting activity is limited to extracerebral tissuesadministration of carbidopa with levodopa makes more levodopa available for transport to the brain.

If you have trouble remembering to take your tabletsask your pharmacist for some hints.

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