Take ponstel with or without food.
Information about Ponstel.
Dosage is based on your medical condition and response to therapyTo reduce your risk of stomach bleeding and other side effectstake this medication at the lowest effective dose for the shortest possible timeDo not increase your dosetake it more frequentlyor take it for a longer time than prescribedThis medication usually should not be taken for more than 7 days at a time.
The elimination half-life of mefenamic acid is approximately two hoursHalf-lives of metabolites I and II have not been precisely reportedbut appear to be longer than the parent compoundThe metabolites may accumulate in patients with renalor hepatic failureThe mefenamic acid glucuronide may bind irreversibly to plasma proteinsBecause both renal and hepatic excretions are significant pathways of eliminationdosage adjustments in patients with renal or hepatic dysfunction may be necessaryPonstel should not be administered to patients with pre-existing renal disease or in patients with significantly impaired renal functionsee WARNINGSRenal Toxicity and Hyperkalemia
Advise patients to stop Ponstel immediately if they develop any type of rash and contact their healthcare provider as soon as possiblesee WARNINGSSerious Skin Reactions
Nonsteroidal anti-inflammatory drugsincluding mefenamic acidmay rarely increase the risk for asometimes fatalheart attack or strokeThis effect does not apply to low-dose aspirinSee Drug Interactions sectionThis effect can happen at any time while taking this drug but is more likely if you take it for a long timeThe risk may be greater if you have heart disease or increased risk for heart diseasefor exampledue to smokingfamily history of heart diseaseor conditions such as high blood pressure or diabetesDo not take this drug right before or after heart bypass surgeryCABGAlsothis drug may rarely cause seriousrarely fatalbleeding from the stomach or intestinesThis bleeding can occur withoutwarning symptoms at any time during treatment.
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