Hydroxychloroquine may interfere with .
Information about Chloroquine.
Radioactively tagged chloroquine administered intravenously to pregnant pigmented CBA mice passed rapidly across the placenta and accumulated selectively in the melanin structures of the fetal eyesIt was retained in the ocular tissues for five months after the drug had been eliminated from the rest of the body 2There are no adequate and well-controlled studies evaluating the safety and efficacy of chloroquine in pregnant womenUsage of chloroquine during pregnancy should be avoided except in the suppression or treatment of malaria when in the judgment of the physician the benefit outweighs the potential risk to the fetus.
Maculopathy and macular degeneration have been reported and may be irreversiblesee WARNINGSirreversible retinal damage in patients receiving long-term or high-dosage 4-aminoquinoline therapyvisual disturbancesblurring of vision and difficulty of focusing or accommodationnyctalopiascotomatous vision with field defects of paracentralpericentral ring typesand typically temporal scotomase.gdifficulty in reading with words tending to disappearseeing half an objectmisty visionand fog before the eyesReversible corneal opacities have also been reported.
Take chloroquine for the entire length of time prescribed by your doctorIf you are taking this medicine to treat malariayour symptoms may get better before the infection is completely treated.
Chloroquine is sometimes given only once per weekChoose the same day each week to take this medication if you are on a weekly dosing schedule.
Chemicallyit is 7-chloro-44diethylamino1-methylbutyl]aminoquinoline phosphate1:2and has the following structural formula:
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