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There are limited post-marketing data on the use of domperidone in pregnant womenStudies in animals have shown reproductive toxicity at maternally toxic dosessee section 5.3Motilium should only be used during pregnancy when justified by the anticipated therapeutic benefit.
Patients with underlying cardiovascular risk factors may be at higher riskincluding people taking any medicines known to prolong the QT intervalDomperidone should not be used with medicines that prolong QT interval or with medicines that . inhibit CYP3A4Additionallydomperidone should not be used in patients with moderate to severe hepatic impairment.
For the short term treatment in adults of1Symptomsassociated with idiopathic or diabetic gastroparesis(once control of diabetes has been established by diet and/or insulinattempt should be made to discontinue MOTILIUM2Intractable nausea and vomiting from any cause.
Talk to a doctor straight away if you experience dizzinessfaintingchest painor a rapidflutteringor pounding heartbeat while taking domperidone.
Domperidone is associated with a small increased risk of serious cardiac side effectsThe UK Commission on Human MedicinesCHMhas concluded that products containing domperidone meet the requirements for prescription-only supplyTherefore people need to have a medical assessment before taking domperidone to determine if it is suitable for them.
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in fact, motilium will not stop vomiting during poisoning, because it is caused by the intake of toxic substances into the blood from the intestine, and not by the disorder of the stomach.var 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