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I was taken off the imuran because of using it so long, this was one of the side effects.

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Imuraneither alone or more usually in combination with corticosteroids and/or other drugs and procedureshas been used with clinical benefitwhich may include reduction of dosage or discontinuation of corticosteroidsin a proportion of patients suffering from the following:

Imuran should not be given to patients who are pregnant or likely to become pregnant without careful assessment of risk versus benefit.

As there is in vitro evidence that aminosalicyclate derivatives(egolsalazinemesalazine or sulphasalazineinhibit the TPMT enzymethey should be administered with caution to patients receiving concurrent Imuran therapysee 4.4 Special Warning and Special Precautions for Use

A gastrointestinal hypersensitivity reaction characterized by severe nausea and vomiting has been reportedThese symptoms may also be accompanied by diarrhearashfevermalaisemyalgiaselevations in liver enzymesand occasionallyhypotensionSymptoms of gastrointestinal toxicity most often develop within the first several weeks of therapy with IMURAN and are reversible upon discontinuation of the drugThe reaction can recur within hours after re-challenge with a single dose of IMURAN.

Take a missed dose as soon as you think about itIf it is close to the time for your next doseskip the missed dose and go back to your normal timeDo not take 2 doses at the same time or extra doses.

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