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LANOXIN may cause severe sinus bradycardia or sinoatrial block particularly in patients with pre-existing sinus node disease and may cause advanced or complete heart block in patients with pre-existing incomplete AV blockConsider insertion of a pacemaker before treatment with digoxin.
Plasma digoxin concentrations in patients with acute hepatitis generally fall within the range of profiles in a group of healthy subjects.
Digoxin increases the strength and efficiency of heart contractionsand is useful in the treatment of heart failure and control the rate and rhythm of the heartIt is extracted from the leaves of a plant called digitalis lanataDigoxin increases the force of contraction of the muscle of the heart by inhibiting the activity of an enzymeATPasethat controls movement of calciumsodiumand potassium into heart muscleCalcium controls the force of contractionInhibiting ATPase increases calcium in heart muscle and therefore increases the force of heart contractionsDigoxin also slows electrical conduction between the atria and the ventricles of the heart and is useful in treating abnormally rapid atrial rhythms such as atrial fibrillationatrial flutterand atrial tachycardiaAbnormally rapid atrial rhythms can be caused by heart attacksexcessive thyroid hormonesalcoholisminfectionsand many other conditionsDuring rapid atrial rhythmselectrical signals from the atria cause rapid contractions of the ventriclesRapid ventricular contractions are inefficient in pumping blood containing oxygen and nutrients to the bodycausing symptoms of weaknessshortness of breathdizzinessand even chest painDigoxin alleviates these symptoms by blocking the electrical conduction between the atria and ventriclesthus slowing ventricular contractionsThe FDA approved digoxin in 1975.
Take one large single dose and then begin your maintenance dose or take a smaller dose each day for a week and then begin your maintenance dose.
The Patient Information LeafletPILis the leaflet included in the pack with a medicineIt is written for patients and gives information about taking or using a medicineIt is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
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