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Laboratory Test FindingsSerum ElectrolytesHyperkalemia and hyponatremia have occurredsee Precautions
Renovascular HypertensionSome patients with renovascular hypertensionespecially those with bilateral renal artery stenosis or stenosis of the artery to a solitary kidneymay develop an exaggerated response to the first dose of lisinoprilThereforea lower starting dose of 2.5 or 5 mg is recommendedThereafterthe dosage may be adjusted according to the blood pressure response.
Acute Myocardial InfarctionTreatment with lisinopril may be started within 24 hours of the onset of symptoms in hemodynamically stable patientsPatients should receiveas appropriatethe standard recommended treatments such as thrombolyticsASA and beta blocker(ssee IndicationsAcute Myocardial Infarction
While the mechanism through which lisinopril lowers blood pressure is believed to be primarily the suppression of the renin-angiotensin-aldosterone systemlisinopril also lowers blood pressure in patients with low-renin hypertension.
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