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Tell your doctor right away if any of these rare but . very serious side effects occurblack/bloody stoolssevere stomach/abdominal painyellowing eyes or skindark urinemental/mood changesmuscle weakness/spasm.
No residual cardiac abnormalitiesas evidenced by electrocardiogram or echocardiogram appear to be present in patients surviving episodes of apparent cardiac toxicity associated with high doses of cyclophosphamide.
Nausea and vomiting commonly occur with cyclophosphamide therapyAnorexia andless frequentlyabdominal discomfort or pain and diarrhea may occurThere are isolated reports of hemorrhagic colitisoral mucosal ulceration and jaundice occurring during therapyThese adverse drug effects generally remit when cyclophosphamide treatment is stopped.
The rate of metabolism and the leukopenic activity of cyclophosphamide reportedly are increased by chronic administration of high doses of phenobarbital.
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