Viramune xr has not been evaluated in subjects with hepatic impairment.
Information about Viramune
The FDA has approved several generic formulations of nevirapine for use in the United StatesIt has grantedtentative approvedstatus to a number of other generic formulationsmaking them eligible for purchase and use as part of the President’s Emergency Plan for AIDS ReliefPEPFARin resource-limited countries.
The dose should not be increased to the maintenance dose until any rash has clearedIf the patient cannot switch tothe full dose within four weeks of starting Viramunealternative treatments should be sought.
It is not recommended to co-administer ketoconazole and Viramunesee section 4.4
The following adverse reactions which may be causally related to the administration of Viramune have been reportedThe frequencies estimated are based on pooled clinical study data for adverse reactions considered related to Viramune treatment.
If switching from nevirapine IR formulation200 mg BIDto XR formulationstart XR tablet400 mg QDwithout lead-in dosage adjustment)
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