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What is a package insertA package insert is required by the FDA and contains a summary of the essential scientific information needed for the safe and effective use of the drug for healthcare providers and consumersA package insert typically includes information regarding specific indicationsadministration schedulesdosingside effectscontraindicationsresults from some clinical trialschemical structurepharmacokinetics and metabolism of the specific drugBy carefully reviewing the package insertyou will get the most complete and current information about how to safely use this drugIf you do nothave the package insert for the drug you are usingyour pharmacist or physician may be able to provide you with a copy.
Patients on corticosteroid therapy may exhibit a diminished response to toxoids and live or inactivated vaccines due to inhibition of antibody responseCorticosteroids may also potentiate the replication of some organisms contained in live attenuated vaccinesRoutine administration of vaccines or toxoids should be deferred until corticosteroid therapy is discontinued if possiblesee WARNINGSInfectionsVaccination
Bradycardiacardiac arrestcardiac arrhythmiascardiac enlargementcirculatory collapsecongestive heart failurefat embolismhypertensionhypertrophic cardiomyopathy in premature infantsmyocardial rupture following recent myocardial infarctionsee WARNINGSCardio-renaledemapulmonary edemasyncopetachycardiathromboembolismthrombophlebitisvasculitis.
Bradycardiacardiac arrestcardiac arrhythmiascardiac enlargementcirculatory collapsecongestive heart failurefat embolismhypertensionhypertrophic cardiomyopathy in premature infantsmyocardial rupture following recent myocardial infarctionsee WARNINGSCardio-renaledemapulmonary edemasyncopetachycardiathromboembolismthrombophlebitisvasculitis.
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