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Rivastigmineas a cholinesterase inhibitoris likely to exaggerate succinylcholine-type muscle relaxation during anesthesia.
Some people have had a serious skin reaction called allergic contact dermatitisACDwhen using EXELON PATCHStop using EXELON PATCH and call your health care provider right away if you experience reactions that spread beyond the patch sizeare intense in natureand do not improve within 48 hours after the patch is removedSymptoms of ACD may be intense and include itchingrednessswellingwarmth or tenderness of the skinor peeling or blistering of the skinwhich may oozedrainor crust over.
Asthmachronic obstructive pulmonary diseaseCOPDor other breathing disorder;
Because rivastigmine increases cholinergic activityuse of rivastigmine may have vagotonic effects on heart ratee.gbradycardiaThe potential for this action may be particularly important in patients with sick sinus syndrome or other supraventricular cardiac conduction conditionsIn clinical trialsrivastigmine was not associated with any increased incidence of cardiovascular adverse eventsheart rate or blood pressure changesor electrocardiogramECGabnormalitiesSyncopal episodes have been reported in 3of patients receiving 6 mg to 12 mg per day of EXELONcompared to 2of placebo patients.
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