Do not try to inhale the spray or breathe in too deeply, as nasonex mometasone works when in comes into contact with the inside surfaces of the nose, not the throat or lungs.
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Treatment with higher than recommendeddoses may result in clinically significant adrenal suppressionIf there is evidence for higher than recommended doses being usedthen additional systemic corticosteroid cover should be considered during periods of stress or elective surgery.
Although NASONEX Nasal Spray will control the nasal symptoms in most patientsthe concomitant use of appropriate additional therapy may provide additional relief of other symptomsparticularly ocular symptoms.
Mometasone furoate increased chromosomal aberrations in an in vitro Chinese hamster ovary-cell assaybut did not increase chromosomal aberrations in an in vitro Chinese hamster lung cell assayMometasone furoate was not mutagenic in the Ames test or mouse-lymphoma assayand was not clastogenic in an in vivo mouse micronucleus assay and a rat bone marrow chromosomal aberration assay or a mouse male germ-cell chromosomal aberration assayMometasone furoate also did not induce unscheduled DNA synthesis in vivo in rat hepatocytes.
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