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Coadministration with other lipid-lowering therapyConsider dose reduction if combined with niacin or fenofibratebecause of increased risk for skeletal muscle effects.

In rare casesrosuvastatin can cause a condition that results in the breakdown of skeletal muscle tissueleading to kidney failureThis condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidismunderactive thyroid

Coadministration with other lipid-lowering therapyConsider dose reduction if combined with niacin or fenofibratebecause of increased risk for skeletal muscle effects.

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