Lilly also marketed fluoxetine as sarafem which has been licensed to an- other uses of the same med-icine.
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Patients should be advised of the signs and symptoms associated with serotonin syndrome that may include mental status changesfor exampleagitationhallucinationsdeliriumand comaautonomic instabilityfor exampletachycardialabile blood pressuredizzinessdiaphoresisflushinghyperthermianeuromuscular changesfor exampletremorrigiditymyoclonushyperreflexiaincoordinationseizuresand/or gastrointestinal symptomsfor examplenauseavomitingdiarrheaPatients should be cautioned to seek medical care immediately if they experience these symptoms.
Many drugs besides fluoxetine may affect the heart rhythmQT prolongationincluding pimozide and thioridazineamong others.
It should be noted that SARAFEM is not approved for treating any indication in the pediatric population.
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