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In bioequivalence studies of actoplus met 15 mg 500 mg and 15 mg 850 mg, the area under the curve auc and maximum concentration c max of both the pioglitazone and the metformin component following a single dose of the combination tablet were bioequivalent to actos 15 mg concomitantly administered with glucophage 500 mg or 850 mg respectively tablets under fasted conditions in healthy subjects.
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If you need to have any type of x-ray or ct scan using a dye that is injected into your veins, you will need to temporarily stop taking actoplus met.
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