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PLAQUENIL is useful in patients with the following disorders who have not responded satisfactorily to drugs with less potential for serious side effectslupus erythematosuschronic discoid and systemicand acute or chronic rheumatoid arthritis.

Not for treating complicated malariaNot effective against chloroquineor hydroxychloroquine-resistant strainsNot for preventing relapses of Pvivax or PovaleNot for treatment and prophylaxis in chloroquine-resistant areas.

Hydroxychloroquine is also used to treat and prevent certain types of malariaIt may also be used for the treatment of lupus.

PregnancyHydroxychloroquine crosses the placenta during pregnancy and may cause harm to the developing baby if it is taken by the mother during pregnancyThis medication should notbe used during pregnancy unless the benefits outweigh the risksIf you become pregnant while taking this medicationcontact your doctor immediately.

The incidence of corneal changes and visual side effects appears to be considerably lower with hydroxychloroquine than with chloroquine.

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